Bio-identical Hormones: Estrogen Metabolism
- E1 (estrone) — Main estrogen the body makes post-menopausally. High levels may increase a woman's risk of breast cancer.
- E2 (estradiol) — Provides over 400 functions in the body, the most potent estrogen.
- E3 (estriol) — The least powerful and most beneficial, comprises 80-90% of human estrogen.

With efficient estrogen metabolism, this results in the predominance of 2-hydroxy and 2-methoxyestrogens. These "good estrogen" metabolites function as antioxidants, and have the power to eliminate damaged or cancerous cells throughout the body.
Inefficient estrogen metabolism results in a predominance of 16-hydroxy estrone and 4-hydroxy estrone. These "bad estrogen" metabolites act negatively to allow oxidation, to damage DNA, and to promote cancer.
How Can You Promote Healthy Estrogen Metabolism?
- Moderate exercise
- Increase cruciferous vegetables in your diet, i.e., broccoli and cauliflower
- Flax
- High protein diet
- Eat organic, pesticide-free foods whenever possible
- Weight loss — estrogen production/storage occurs in fat cells
- Decrease alcohol consumption — alcohol interferes with the body's ability to detoxify estrogen!
- Try one of our natural supplements to promote healthy estrogen metabolism:
- DIM — Works by increasing good estrogen metabolites (2-hydroxyestrone), and is very protective against estrogen dominant cancers.
Dr. Brenner, MD & Associates - Women's Health Care and Gynecology - is pleased to serve patients from the following towns: Anderson, Blue Ash, Cincinnati, Fairfield, Finneytown, Hamilton, Harrison, Hyde Park, Indian Hill, Landen, Lebanon, Liberty Township, Loveland, Madeira, Mariemont, Mason, Middletown, Milford, Monroe, Montgomery, Norwood, Sharonville, Springboro, Trenton, West Chester. |